Any comments, please. Docetaxel contains alcohol. My concern is that with my weight, history of smoking and alcohol my body will not tolerate all of this. You may not be able to become pregnant or father a child after treatment with this drug. The typical docetaxel product contains 18% alcohol by weight. The FDA is revising the labels of all docetaxel products … Docetaxel contains alcohol. The amount of alcohol in each dose varies according to the manufacturer. I am a small women (112 lbs. Discuss with your doctor if there is any reason you shouldn’t take this. Moreover, alcohol is a known risk factor for developing certain types of cancer, therefore it is very important you do not drink alcohol without being cleared to do so by your doctor first. Selection of a preparation with lower alcohol content is advisable for certain patients. Alcohol is used to dissolve the active ingredients so that the drug can be given intravenously. Docetaxel contains ethanol, or alcohol, explains the agency in a drug safety communication. The need for an alcohol-free formulation followed a drug safety communication issued by the FDA in June 2014 regarding the risk of intoxication with the intravenous ethanol-containing formulation of docetaxel, which is marketed as generic docetaxel and under the brand names Taxotere, Docefrez, and Docetaxel Injection. For this reason, it is recommended that patients must be aware of an increased risk of getting drunk even when drinking a glass of wine or a … Your blood alcohol level may be above the legal limit after you have the treatment. The company notes that the alcohol content of other docetaxel formulations, including Taxotere, ranges from 2.0 to 6.4 g in a 200-mg dose. If this is a problem for you, tell your doctor, nurse or pharmacist. Docetaxel Injection and administration of appropriate therapy (5.4) Contraindicated if history of severe hypersensitivity reactions to docetaxel or to drugs formulated with polysorbate 80 (4) Severe fluid retention may occur despite dexamethasone (5.5) INDICATIONS AND USAGE Docetaxel Injection is a microtubule inhibitor indicated for: Docetaxel is a taxane product indicated for the treatment of breast cancer, non-small cell lung cancer, prostate cancer, gastric adenocarcinoma, and head and neck cancer. It may affect your ability to drive or use machines. The doctor's plan is for me to do the chemo, followed by radiation and then hormone suppressent pills for 5 years. Products Lidoderm® Versatis® Non-Alcohol Docetaxel Injection; Docetaxel Injection Non-Alcohol Formula. Alcohol can harm your liver and interact with certain medications. Docetaxel, a commonly used IV chemotherapeutic agent, can produce alcohol intoxication. That's about 23% by volume (because ethanol is less dense than water: 0.789 … It has a role as an antineoplastic agent, a photosensitizing agent and an antimalarial. Docetaxel anhydrous is a tetracyclic diterpenoid that is paclitaxel with the N-benzyloxycarbonyl group replaced by N-tert-butoxycarbonyl, and the acetoxy group at position 10 replaced by a hydroxy group. It is best not to drive or operate machinery for a few hours after having this treatment, even if you feel okay. Similarly, drinking alcohol while under treatment with docetaxel may quickly add up to the amount of this substance that the patient was injected with during the infusion. In June 2014, the … ), and have smoked and used alcohol for most of my life. Loss of fertility.
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